Scientific References
Clinical Research & Studies Supporting LipoVive
At LipoVive, we believe in transparency and science-backed formulations. This page contains comprehensive scientific references and clinical studies that support the effectiveness of the key ingredients in our formula. Each ingredient has been carefully selected based on peer-reviewed research and clinical trials published in respected medical and scientific journals.
Research Disclaimer:
The following references are provided for educational purposes. While these studies support the individual ingredients found in LipoVive, they do not constitute medical advice. Individual results may vary. Always consult with a healthcare professional before starting any new supplement regimen.
Clinical Studies by Category
Green Tea Extract & Weight Loss
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Dulloo AG, Duret C, Rohrer D, et al. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr. 1999 Dec;70(6):1040-5. doi: 10.1093/ajcn/70.6.1040.PMID: 10584049
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Hursel R, Viechtbauer W, Westerterp-Plantenga MS. The effects of green tea on weight loss and weight maintenance: a meta-analysis. Int J Obes (Lond). 2009 Sep;33(9):956-61. doi: 10.1038/ijo.2009.135.PMID: 19597519
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Nagao T, Hase T, Tokimitsu I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring). 2007 Jun;15(6):1473-83. doi: 10.1038/oby.2007.176.PMID: 17557985
Apple Cider Vinegar & Metabolic Health
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Kondo T, Kishi M, Fushimi T, et al. Vinegar intake reduces body weight, body fat mass, and serum triglyceride levels in obese Japanese subjects. Biosci Biotechnol Biochem. 2009 Aug;73(8):1837-43. doi: 10.1271/bbb.90231.PMID: 19661687
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Petsiou EI, Mitrou PI, Raptis SA, Dimitriadis GD. Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight. Nutr Rev. 2014 Oct;72(10):651-61. doi: 10.1111/nure.12125.PMID: 25168916
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Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care. 2004 Jan;27(1):281-2. doi: 10.2337/diacare.27.1.281.PMID: 14694010
Berberine HCL & Weight Management
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Zhang Y, Li X, Zou D, et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65. doi: 10.1210/jc.2007-2404.PMID: 18397984
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Hu Y, Ehli EA, Kittelsrud J, et al. Lipid-lowering effect of berberine in human subjects and rats. Phytomedicine. 2012 Jul 15;19(10):861-7. doi: 10.1016/j.phymed.2012.05.009.PMID: 22739408
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Lee YS, Kim WS, Kim KH, et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes. 2006 Aug;55(8):2256-64. doi: 10.2337/db06-0006.PMID: 16873688
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Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008 May;57(5):712-7. doi: 10.1016/j.metabol.2008.01.013.PMID: 18442638 | PMCID: PMC2410097
Ginger Root & Metabolism
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Mansour MS, Ni YM, Roberts AL, et al. Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: a pilot study. Metabolism. 2012 Oct;61(10):1347-52. doi: 10.1016/j.metabol.2012.03.016.PMID: 22538118 | PMCID: PMC3408800
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Maharlouei N, Tabrizi R, Lankarani KB, et al. The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2019;59(11):1753-1766. doi: 10.1080/10408398.2018.1427044.PMID: 29393665
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Ebrahimzadeh Attari V, Ostadrahimi A, Asghari Jafarabadi M, et al. Changes of serum adipocytokines and body weight following Zingiber officinale supplementation in obese women: a RCT. Eur J Nutr. 2016 Sep;55(6):2129-36. doi: 10.1007/s00394-015-1027-6.PMID: 26318445
Cinnamon Bark & Blood Sugar Regulation
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Khan A, Safdar M, Ali Khan MM, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care. 2003 Dec;26(12):3215-8. doi: 10.2337/diacare.26.12.3215.PMID: 14633804
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Roussel AM, Hininger I, Benaraba R, et al. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr. 2009 Feb;28(1):16-21. doi: 10.1080/07315724.2009.10719754.PMID: 19571154
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Qin B, Panickar KS, Anderson RA. Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes. J Diabetes Sci Technol. 2010 May 1;4(3):685-93. doi: 10.1177/193229681000400324.PMID: 20513336 | PMCID: PMC2901047
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Ziegenfuss TN, Hofheins JE, Mendel RW, et al. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr. 2006 Dec 28;3(2):45-53. doi: 10.1186/1550-2783-3-2-45.PMID: 18500972 | PMCID: PMC2129161
Chromium & Insulin Function
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Anderson RA, Cheng N, Bryden NA, et al. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes. 1997 Nov;46(11):1786-91. doi: 10.2337/diab.46.11.1786.PMID: 9356027
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Anton SD, Morrison CD, Cefalu WT, et al. Effects of chromium picolinate on food intake and satiety. Diabetes Technol Ther. 2008 Oct;10(5):405-12. doi: 10.1089/dia.2007.0292.PMID: 18715218 | PMCID: PMC2753428
Comprehensive Metabolic & Weight Loss Reviews
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Hursel R, Westerterp-Plantenga MS. Thermogenic ingredients and body weight regulation. Int J Obes (Lond). 2010 Apr;34(4):659-69. doi: 10.1038/ijo.2009.299.PMID: 20142825
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Tabrizi R, Saneei P, Lankarani KB, et al. The effects of caffeine intake on weight loss: a systematic review and dose-response meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2019;59(16):2688-2696. doi: 10.1080/10408398.2018.1507996.PMID: 30335479
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Onakpoya I, Terry R, Ernst E. The use of green coffee extract as a weight loss supplement: a systematic review and meta-analysis of randomised clinical trials. Gastroenterol Res Pract. 2011;2011:382852. doi: 10.1155/2011/382852.PMID: 20871849 | PMCID: PMC2943088
Important Note:
These references represent independent scientific research on individual ingredients. The specific LipoVive formulation has been developed based on these studies, but the product itself has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Results may vary based on individual factors.